Millions of people in Israel and Iran are bracing for an escalation in fighting between the two countries after Israel launched a wave of strikes overnight.
Israel's military said it had hit multiple nuclear sites, and killed top Iranian commanders.
Local media reported a number of drones launched by Iran in response were successfully intercepted.
In a recorded statement, Israel's Prime Minister Benjamin Netanyahu vowed to destroy Iran's nuclear capability, which he said posed a "clear and present danger" to his country's survival.
Meanwhile, Iranian President Masoud Pezeshkian said Tehran's response to Israeli attacks would be "legitimate and powerful".
Read live updates on this story.